The Last Story and Xenoblade are set for 2010 releases in Japan.
The Last Story, which is being co-developed by Nintendo and Mistwalker, is an attempt at a "new form of RPG" according to a translation provided by Andriasang. The official site does not give a firm release date, only saying the game will release in 2010. A developer blog will start up in March.
The second RPG, Xenoblade, is developed by Monolift Soft. The game was previously known as Monado: The Beginning of the World. The newly launched website for the game is light on content and details, but a 2010 date can be seen, hinting at a 2010 release.
Nintendo World Report will have more information on these games as it becomes available.