My big money prediction? F-Zero 3DS from Nd Cube.
Instead of a bullet-pointed list, which I had halfway done, I'm going to layout how I think the Nintendo E3 Presentation will go. Now, prepare to be transported to June 7 at around 9:05 a.m. PDT (They always start a little late.).
To kick off the show, Nintendo of America President Reggie Fils-Aime will take the stage, and spout off some sort of brief overview of the whole shebang, something about how Nintendo rocks our faces off. Then, he'll go right into 3DS announcements, showing trailers for Super Mario 3D and Mario Kart 3D. They'll have some sort of elaborate ruse with Mario Kart, showing off StreetPass by maybe having Reggie be StreetPassed by Shigeru Miyamoto, and then having some sort of witty repartee. The big surprise, though, will be a new F-Zero 3DS game from Nd Cube, set for an early 2012 release.
Third-party games will also get highlighted, including Konami's Metal Gear Solid 3D, Activision's GoldenEye 3D, and Square Enix's Kingdom Hearts 3D. To finish off the 3DS-heavy segment, Reggie will announce two release dates: a mid-July release for Star Fox 64 3D, and a late August release for Kid Icarus: Uprising. The Uprising announcement will lead into another reveal: Smash Bros. on 3DS, coming from Game Arts in 2012.
Next up is the eShop. Nintendo will spout niceties about last night's launch, and then reveal that you can watch trailers of all the games announced on the eShop right after the end of the show. They'll also unveil new eShop titles from Capcom (Mega Man 11), Konami (Contra), and Ubisoft (Petz). Then they'll showcase the big Nintendo eShop release - a Wario Land title in the same vein as the Virtual Boy game. GoodFeel is developing. It'll be coming this fall.
Wii will be next up, and the show will slow to a grinding halt as they show off Wii Play Motion briefly. They'll save face by talking Zelda afterwards, with Skyward Sword getting a new trailer, focusing on dungeons. Then, they'll unveil the 25th Anniversary Zelda compilation, coming to 3DS this fall. It'll feature 3DS Classic versions of Zelda I, II, and a Link to the Past. It'll be budget priced.
There will be some quick hits, including a reveal of the localization of Xenoblade and The Last Story. The new Kirby DS and Wii games, as well as Pokémon Typing and Layton 4, will likely not be mentioned, but will be playable on the show floor and show up in press kits as having fall releases.
To close the show, Café will be revealed, but not given a full name. The presentation will focus solely on the new controller. Demos will be made up of tech demos and a few Nintendo and third-party games (Mario, Pikmin, Madden, and/or Call of Duty). A game from Next Level Games, possibly Wave Race, will be a highlight and a confirmed launch title. The release date will be ambiguous, causing speculation that it might come out in 2011. It won't, though spring 2012 is a possibility depending on how the 3DS fares this fall.
Like previous years, girls and demos will pop out of the ground. This year, they'll showcase Super Mario 3D and Skyward Sword.