Super Mario Bros. Nation: Use the remote to control all of the character movements. Tilting to run and straffe, twisting to turn, moving the piece horizontally to roll, moving the piece vertically to jump, fly, or climb, pull the piece back to pick up objects, push the piece forward to throw objects, etc. The analog stick nunchuck controls the camera similar to how the camera controlled in Zelda WW or SMSunshine though improved and able to pan further out. Online multiplayer platforming racing with Mario, Luigi, Peach, Toad, DK, Yoshis, and others.
Zelda: The analog stick nunchuck controls character movements, the camera is at a 3/4 view, and the remote piece controls sword, spear, shield, hammer, axe, bow, etc. Online coop with Zelda, Gannondorf, and Link; up to six players when a character wields the four sword.
Castlevania: Straight up remake of Casltevania with Simon Belmont using the remote to control all whip and sword action. Deep rpg system similar to 2d Castlevanias since SotN. Character controls done with the nunchuck analog stick.
New 007 using the remote piece; basically any shooter using the remote piece is going to be unmatched by anything. Just think of this; you can zoom in and out simply by moving the remote in and out in 3d. I believe they should have put an analog stick or trackball on each vcr remote so a game like Zelda or Mario can play one handed, but I am willing to play a shooter with two remote pieces (using the dpad for movement like in a pc game). Who is to say they won't make Zelda a dual wielding game, perhaps as an option.
How about a game in which one remote acts as a 3d stick for movement like I described Mario Bros, and the other remote controls the hand movements.
The games can be abstractly controlled too. You can make a game in which you run by moving the remotes up and down in 3d as if you were running.
My dream game contest idea: Basically a vampire game using the nunchuck attachement with the controls I described for Mario Bros. at the beginning of my post with a puzzle based adventure more like Zelda in an open 3d fantasy world with heavy emphasis on exploration, graphic cel shading, superdeformed character models, flying, running seventy mph on all fours, necromancing (your blood can do some spectacular things), voluntary transformations, and involuntary transformations based on lunar cycles. You can pick up weapons, but rarely will you find something worth keeping or hiding away to play with later. A good example of something you wouldn't throw away: a black unicorn horn. If you simply want to cut some things up though you can pick up any sword, spear, staff, etc in the game. The b button will control that attack locking onto an enemy of your choice, switching character control to the analog stick and the camera to first person where you can swing your sword however you like. I must say you would be able to go into first person mode using the analog stick during normal gameplay. The majority though of the game will not require sword play, it would be an option as turning into shadows for example would allow you to use strategy when fighting. With a single transformation you can terrify your human enemy to death or turn to fog and posses him/her for a little while. Your magic and life would be in one meter in the corner of the screen simply replenished by eating something alive, not neccesarily a human, but you can get a lot more energy from a single human than from eating a hundred chickens.