If the American media reports on the 3DS as they did the iPad, $300 might work for Nintendo, but $250 will make it seem like a bargain. Not only does it play highly detailed games, but in plays them in 3D without glasses (a rather novel concept to most people who have not been following the 3DS's development), and it also has a 3D camera, another novelty that will be big in the future when glasses-free, 3D digital picture frames start arriving using the same tech as the 3DS screen. Though, I wonder if Nintendo should have used higher res for the 3D camera(s).
My biggest fear/anticipation is of the mid-life 3DS redesign. It was so well received and doted on at E3 that Sony has to be thinking of a 3D PSP2, and don't be surprised if next year's ipod/iphone lineup isn't also 3D. In order to compete, I think Nintendo is going to have make serious changes to the 3DS, including higher res cameras, more robust internet features, and maybe even a 4G antenna (AT&T and Verizon are launching their 4G's networks starting small later this year, and fully next year).
What's up with the 3DS dock? Is it inductive charging? Will it operate like the touchstone for the Palm Pre, and change the face and functions of the 3DS when it's on the dock?
Also there are a lot of things going to be bundled in with the 3DS, and I wonder how much NOA is going to push the "augmented reality" cards. Such gimmicks (for lack of a word with less negative connotation) work better in Japan, (as would tag mode since it so much more densely populated and their adults are less embarrassed to be seen playing video games in public) like that card reader attachment for the gba. But I said all that because I was going to say that a "full" game (as opposed to a "3DSware" type of game, or demos) seems unlikely. Demos + built-in fun software (like the Mii stuff, and other 3D camera apps) + AR cards + ability to stream 3D content (hopefully not just from dedicated server, but also like youtube3D and ESPN3D) + 2GB memory card = enough bundled in already, at least imho.
Also, the design is slightly different; the nub is no longer the color of the system.