I would think that the core gamers have already shown a marked disinterest for the game. If Ancel really wants to make a game about nonviolent resistance, then he really should put it on the Wii where the development costs will be cheaper (and thus risk will be lower for all involved), and where the userbase includes people who are more open to the concept of "not-a-bald-space-marine" and also includes new people who haven't already rejected the game ocne before.
From a business perspective with an eye to ensuring that this game actually manages its risks and reaches completion, and has a chance to improve on the performance of its predecessor, the Wii is the only console that makes sense.