I'd definately recommend Zack n Wikki for your GF/Wife as well!  My wife hated games until Zach n Wikki arrived.  Once she got her hands on it, we played the entire thing together, oftentimes w/ her asking starting it up.  It was a lot of fun, and now she's even growing an addiction to Mario Kart Wii, Professor Layton, and Word Coach!  Thanks Capcom!