While I personally believe there's more DLC beyond Mewtwo, it isn't unreasonable to think there may not be considering this is Nintendo we're talking about. For better or worse, Nintendo often bucks conventional wisdom. DLC seems inevitable, and I believe Nintendo realizes the potential. However, it might not even come to that. Nintendo has shown a tremendous amount of loyalty to its own talent and those close to the company. If Sakurai said no DLC for whatever reason (e.g. burn out, troll etc.), I see Iwata obliging. Sure, there's tons of money to be made, but if it means doing so without Sakurai's help or blessing, Nintendo would nix DLC plans right then and there. While I'd like to see Sakurai take more of a producer/supervisor role in a sequel, I don't think it's wise to alienate him. For that reason, I can see this going either way.