| Name |
System |
Subsystem |
Players |
Genre |
Release Date |
| Sabre Wulf | Game Boy Advance | | 1 | Action | Jun 9, 2004 |
| Samurai Jack: The Amulet of Time | Game Boy Advance | | 1 | Action | Mar 30, 2003 |
| Scooby-Doo 2: Monsters Unleashed | Game Boy Advance | | 1 | Action | Mar 16, 2004 |
| Scooby-Doo! Unmasked | Game Boy Advance | | 1 | Action | Sep 12, 2005 |
| Scrabble Blast! | Game Boy Advance | | 1 - 2 | Party/Parlor | May 3, 2005 |
| Scurge: Hive | Game Boy Advance | | 1 | Adventure | Oct 24, 2006 |
| Sega Smash Pack | Game Boy Advance | | 1 - 2 | Action | Sep 23, 2002 |
| Sennen Kazoku | GBA / WiiU | | 1 | Simulation | Mar 10, 2005 |
| Serious Sam Advance | Game Boy Advance | | 1 - 4 | Shooter | Apr 12, 2004 |
| Shaman King: Legacy of the Spirits | Game Boy Advance | | 1 | Strategy | Feb 8, 2005 |
| Shaman King: Master of Spirits | Game Boy Advance | | 1 | Action | Nov 9, 2004 |
| Shaman King: Master of Spirits 2 | Game Boy Advance | | 1 | Action | Aug 2, 2005 |
| Shark Tale | Game Boy Advance | | | Action | Sep 27, 2004 |
| Shaun Palmer’s Pro Snowboarder | Game Boy Advance | | 1 | Sports | Nov 27, 2001 |
| Shining Force: Resurrection of the Dark Dragon | GBA / WiiU | | 1 | RPG | Jun 8, 2004 |
| Shining Soul | GBA / WiiU | | 1 | RPG | Sep 23, 2003 |
| Shining Soul II | GBA / WiiU | | 1 - 4 | Adventure | Apr 20, 2004 |
| Shrek 2: Beg For Mercy! | Game Boy Advance | | 1 | Action | Oct 27, 2004 |
| Shrek 2 (GBA) | Game Boy Advance | | 1 | Action | May 4, 2004 |
| Shrek Smasn 'N Crash Racing | Game Boy Advance | | | Racing | Nov 17, 2006 |
| Shrek SuperSlam | Game Boy Advance | | 1 | Fighting | Oct 25, 2005 |
| Shrek the Third | Game Boy Advance | | 1 | Action | May 15, 2007 |
| Sigma Star Saga | Game Boy Advance | | 1 | RPG | Aug 16, 2005 |
| Silent Scope (GBA) | Game Boy Advance | | 1 - 4 | Shooter | Sep 4, 2002 |
| Slime Morimori Dragon Quest | Game Boy Advance | | | RPG | TBA |
| Smashing Drive (GBA) | Game Boy Advance | | 1 | Racing | Nov 1, 2004 |
| Sonic Advance | GBA / WiiU | | 1 - 4 | Action | Feb 3, 2002 |
| Sonic Advance 2 | GBA / WiiU | | 1 - 4 | Action | Mar 9, 2003 |
| Sonic Advance 3 | GBA / WiiU | | 1 - 4 | Action | May 24, 2004 |
| Sonic Advance & Sonic Pinball Party Combo Pack | Game Boy Advance | | 1 - 4 | Action | Nov 2005 |
| Sonic Battle | Game Boy Advance | | 1 - 4 | Fighting | Jan 5, 2004 |
| Sonic the Hedgehog | Game Boy Advance | | | Action | Nov 2006 |
| Soundvoyager | Game Boy Advance | | 1 | Puzzle | Jul 27, 2006 |
| Space Hexcite: Metal Legend EX | Game Boy Advance | | 1 - 2 | Puzzle | Apr 27, 2001 |
| Spider-Man 2 (GBA) | Game Boy Advance | | 1 | Action | Jul 2004 |
| Spider-Man: Battle for New York | Game Boy Advance | | 1 | Action | Nov 14, 2006 |
| Spider-Man: Mysterio's Menace | Game Boy Advance | | 1 | Action | Sep 19, 2001 |
| SpongeBob SquarePants: Creature from the Krusty Krab | Game Boy Advance | | | Action | Q3 2006 |
| SpongeBob SquarePants: Lights, Camera, Pants (GBA) | Game Boy Advance | | 1 - 4 | Action | Q3 2005 |
| Spongebob Squarepants: SuperSponge | Game Boy Advance | | 1 | Action | Nov 5, 2001 |
| Spyro 2: Season of Flame | Game Boy Advance | | 1 | Adventure | Sep 25, 2002 |
| Spyro Orange: The Cortex Conspiracy | Game Boy Advance | | 1 - 4 | Action | Jun 1, 2004 |
| Spyro: Season of Ice | Game Boy Advance | | 1 | Action | Oct 29, 2001 |
| Starsky & Hutch GBA | Game Boy Advance | | 1 | Racing | Mar 2004 |
| Star Wars Ep. III: Revenge of the Sith (GBA) | Game Boy Advance | | 1 - 2 | Action | May 4, 2005 |
| Star Wars Episode II: The New Droid Army | Game Boy Advance | | 1 | Action | Nov 14, 2002 |
| Star Wars: Jedi Power Battles | Game Boy Advance | | 1 | Action | Dec 1, 2001 |
| Star Wars Trilogy: Apprentice of the Force | Game Boy Advance | | 1 - 2 | Action | Sep 2004 |
| Steel Empire | Game Boy Advance | | 1 | Shooter | TBA |
| Strawberry Shortcake: Summertime Adventure | Game Boy Advance | | | Action | Year 2005 |
| Strawberry Shortcake Sweet Dreams | Game Boy Advance | | | Action | Sep 19, 2006 |
| Street Fighter Alpha 3 | Game Boy Advance | | 1 - 2 | Fighting | Dec 1, 2002 |
| Stuart Little 2 | Game Boy Advance | | 1 | Action | Jul 12, 2002 |
| Sudoku | Game Boy Advance | | 1 | Puzzle | Feb 10, 2006 |
| Summon Night: Swordcraft Story | Game Boy Advance | | 1 - 2 | RPG | Jul 2006 |
| Summon Night: Swordcraft Story 2 | Game Boy Advance | | 1 - 2 | RPG | Oct 2006 |
| Super Army War | Game Boy Advance | | 1 | Shooter | Feb 2004 |
| Super Bust-A-Move | Game Boy Advance | | 1 - 2 | Puzzle | Nov 27, 2001 |
| Super Collapse! II | Game Boy Advance | | 1 | Puzzle | Mar 2004 |
| Super Dodge Ball Advance | Game Boy Advance | | 1 - 2 | Sports | Jun 10, 2001 |
| Super Ghouls ‘N’ Ghosts | GBA / WiiU | | 1 | Action | Sep 23, 2002 |
| Superman Returns: Fortress of Solitude | Game Boy Advance | | 1 | Action | Nov 20, 2006 |
| Super Mario Advance | GBA / WiiU | | 1 - 2 | Adventure | Jun 10, 2001 |
| Super Mario Advance 4: Super Mario Bros. 3 | GBA / WiiU | | 1 - 4 | Action | Oct 20, 2003 |
| Super Mario World: Super Mario Advance 2 | GBA / WiiU | | 1 - 4 | Action | Feb 9, 2002 |
| Super Puzzle Fighter II Turbo | Game Boy Advance | | 1 - 2 | Puzzle | Apr 3, 2003 |
| Super Robot Taisen | Game Boy Advance | | 1 | Strategy | Sep 21, 2001 |
| Super Robot Taisen: Original Generation | Game Boy Advance | | | Strategy | Q3 2006 |
| Super Robot Taisen: Original Generation 2 | Game Boy Advance | | | Strategy | Q3 2006 |
| Super Smash Bros. GBA | Game Boy Advance | | | Fighting | Rumor |
| Super Street Fighter II Turbo: Revival | GBA / WiiU | | 1 - 2 | Fighting | Oct 30, 2001 |
| Surf's Up | Game Boy Advance | | 1 - 2 | Sports | Q3 2007 |
| Sword of Mana | Game Boy Advance | | 1 - 2 | Adventure | Dec 1, 2003 |
