Nah, but I do regret getting it close to release and buying many games at full price, only to see them go down to budget levels so quickly.
I have 20 retail games and I have enjoyed all of them. I have played the system for hundreds of hours, and if I didn't own one, I would have missed out on Super Mario 3D World, Nintendo Land, LEGO City Undercover (my favorite LEGO game yet by far), Pikmin 3, etc.
I will say that I will not be a launch buyer for Nintendo's next products, though. Strike one was 3DS. Strike two was Wii U. Fool me once, shame on you. Fool me twice, shame on me, and all that.