OK I'm sorry but DONKEY KONG, people, DONKEY KONG!!!
I've read every single post here and not one person even bothered to mention the idea of a Donkey Kong game. Seriously, where has the love for the big ape gone?
Donkey Kong is still one of Nintendo's top series. Contrary to belief, Jungle Beat sold pretty well, not to mention the GBA ports of the Country games were million sellers last gen. Hell, the first Donkey Konga game on the Gamecube managed to sell a million copies worldwide based on the appeal of DK.
So in other words, there's a good chance Nintendo will announce a Donkey Kong game of some kind at E3. Personally I'd love to either see a sequel to Jungle Beat, or an all new 3d Donkey Kong using the Mario Galaxy engine. As long as Tokyo EAD is being either one, you know the end result will be amazing.