But there's the question of storage space...where a ton of NES or even N64 games will fit on a 256MB Flash card, you'd be lucky to fit just one Saturn game on there.
Okay, I'm talking out my arse, I have no idea how big Saturn games were, but they used CDs, so it's probably safe to say that without going back and recompressing FMVs and stuff, a lot of Saturn games would be big space hogs on the internal memory or even a decent-sized SD card.