As far as launch titles go Nintendo really needs to release quite a diverse range of titles right out of the bag.
By doing this it will attract a large audience and accomodate just about everyone.
Not all the titles need to be blockbusters, hopefully there are a few must haves in their launch. They dont all have to be Nintendo brands either just as long as there is something for everyone.
Id like to see something along the lines of:
1. Platformer: Mario game (Nintendo's biggest franchise everyone knows and recognises)
2. RPG: All new RPG from SquareEnix but if not something from the Tales Series by Namco would suffice

3. Racing: There is alot of awesome racing titles out there something like a Ridge Racer or F-Zero or Wave Race etc.
4. Original: Nintendo needs to bring out something totally original a new franchise that flaunts the available features of the Revoluiton (ie if the controllers have gyroscopes in them bring out a game that uses them)
5. Sports: Baseball or Tennis or Golf or BasketBall or American Football (definately not a fan) or Wrestling... something sport orientated
6. FPS: what can i say look at HALO, People like first person shooters so give the people a first person shooter
7. Music: Dare i say it but a music title DDR not only could this title be marketed as a way to keep fit but it still seems to be quite popular.
8. Puzzler: These games can be quite addictive a new Super Monkey Ball would be cool or even a puzzle bobble (cant get enough of that one)
9. Action: A new Resident Evil or Prince of Persia or Ninja Gaiden or Viewtiful Joe.
10. Fighting: SSBM or Soul Calibur or Punch Out hell even bribe Namco to bring its Tekken series over.
11. Mutliplayer: What i mean by this is a game that is designed to be played with more than one person rather than just an extra on the side. A new Mario Party or X-Men Legends or Final Fantasy CC something that everyone can play together.
12. MMORPG: This is a long shot considering Nintendo's stance on online games but if they could use either their pokemon or animal crossing franchise as a MMORPG it would be a huge selling point for their next console.
Now i do relise that Nintendo couldnt possibly launch a title for every different genre there is, thats why you need to get your 3rd parties working in parallel getting their titles ready for launch to give the consumer a wide selection of titles.