Venom was playable quite extensively in the 2005 GameCube/Xbox/PS2 game Ultimate Spider-Man. During the free roaming missions it played a bit like GTA3, the army came after you fairly quickly I believe. He also had some story missions which featured some of the most horrendous quicktime events I've ever seen. There's a segment where you're hammering the shoulder buttons to wedge open doors, and I swear the controls just don't work. Super frustrating.
I'm still amazed we haven't seen a console-sized Wonder Woman game, but heroes like Spawn, Aquaman, Deadpool, and Teen Titans have. She's super iconic, can be slotted into any timezone (from Ancient Greek to modern day), fits every genre (fantasy, thriller, detective, war, sci-fi) and has a varied moveset to draw from (flight, ranged lasso, sword & shield).
Let's have Platinum make it in the Bayonetta engine.