| Name |
System |
Subsystem |
Players |
Genre |
Release Date |
| Samurai Jack: The Shadow of Aku | GameCube | | 1 | Action | Mar 23, 2004 |
| Scaler | GameCube | | 1 | Action | Nov 17, 2004 |
| Scooby-Doo! Mystery Mayhem | GameCube | | 1 | Adventure | Mar 3, 2004 |
| Scooby-Doo! Night of 100 Frights | GameCube | | 1 | Adventure | Sep 12, 2002 |
| Scooby-Doo! Unmasked | GameCube | | 1 | Action | Sep 12, 2005 |
| SeaWorld: Shamu's Deep Sea Adventures | GameCube | | 1 | Adventure | Nov 1, 2005 |
| Second Sight | GameCube | | 1 - 4 | Shooter | Sep 21, 2004 |
| Sega Soccer Slam | GameCube | | 1 - 4 | Sports | Mar 18, 2002 |
| Serious Sam: Next Encounter | GameCube | | 1 - 4 | Shooter | Apr 12, 2004 |
| Shadow the Hedgehog | GameCube | | 1 - 4 | Action | Nov 15, 2005 |
| Shark Tale | GameCube | | 1 | Action | Sep 27, 2004 |
| Showdown: Legends of Wrestling | GameCube | | 1 - 4 | Fighting | Cancelled |
| Shrek 2 | GameCube | | 1 - 4 | Adventure | May 3, 2004 |
| Shrek Smash 'N Crash Racing | GameCube | | | Racing | Jan 2007 |
| Shrek SuperSlam | GameCube | | 1 - 4 | Fighting | Oct 25, 2005 |
| Skies of Arcadia Legends | GameCube | | 1 | RPG | Jan 27, 2003 |
| Smashing Drive | GameCube | | 1 | Action | Feb 18, 2002 |
| Smuggler's Run: Warzones | GameCube | | 1 - 4 | Action | Aug 7, 2002 |
| Sonic Adventure 2: Battle | GameCube | | 1 - 2 | Action | Feb 11, 2002 |
| Sonic Adventure DX Director's Cut | GameCube | | 1 - 2 | Action | Jun 18, 2003 |
| Sonic Gems Collection | GameCube | | 1 - 2 | Action | Aug 16, 2005 |
| Sonic Heroes | GameCube | | 1 - 2 | Action | Jan 5, 2004 |
| Sonic Mega Collection | GameCube | | 1 - 2 | Action | Nov 10, 2002 |
| Sonic Riders | GameCube | | 1 - 4 | Racing | Feb 21, 2006 |
| Soul Calibur II | GameCube | | 1 - 2 | Fighting | Aug 27, 2003 |
| Space Raiders | GameCube | | 1 - 2 | Action | Apr 6, 2004 |
| Spartan: Total Warrior | GameCube | | 1 | Action | Oct 25, 2005 |
| Speed Kings | GameCube | | 1 - 4 | Action | May 28, 2003 |
| Spider-Man 2 | GameCube | | 1 | Action | Jun 29, 2004 |
| Spider-Man: The Movie | GameCube | | 1 | Action | Apr 15, 2002 |
| SpongeBob And Friends Unite (GC) | GameCube | | 1 - 4 | Action | Q4 2005 |
| SpongeBob SquarePants: Creature from the Krusty Krab | GameCube | | 1 | Action | Q3 2006 |
| SpongeBob Squarepants: Lights, Camera, PANTS! | GameCube | | 1 | Action | Oct 21, 2005 |
| SpongeBob Squarepants: Revenge of the Flying Dutchman | GameCube | | 1 | Action | Nov 21, 2002 |
| Spy Hunter | GameCube | | 1 - 2 | Racing | Nov 3, 2002 |
| Spy Hunter 2 | GameCube | | 1 - 2 | Shooter | Cancelled |
| Spyro: A Hero's Tail | GameCube | | 1 | Action | Nov 2, 2004 |
| Spyro: Enter the Dragonfly | GameCube | | 1 | Action | Nov 8, 2002 |
| SSX 3 | GameCube | | 1 - 2 | Sports | Oct 20, 2003 |
| SSX On Tour | GameCube | | | Sports | Oct 11, 2005 |
| SSX Tricky | GameCube | | 1 - 2 | Sports | Dec 2, 2001 |
| Stage Debut | GameCube | | | | Cancelled |
| Starcraft: Ghost | GameCube | | 1 | Action | Cancelled |
| Star Fox Adventures | GameCube | | 1 | Adventure | Sep 22, 2002 |
| Star Fox: Assault | GameCube | | 1 - 4 | Shooter | Feb 14, 2005 |
| Starsky & Hutch | GameCube | | 1 - 2 | Racing | Aug 30, 2004 |
| Star Soldier | GameCube | | 1 - 2 | Shooter | Jul 10, 2003 |
| Star Wars: Bounty Hunter | GameCube | | 1 | Action | Dec 7, 2002 |
| Star Wars Jedi Knight II: Jedi Outcast | GameCube | | 1 - 2 | Shooter | Nov 20, 2002 |
| Star Wars Rogue Squadron III: Rebel Strike | GameCube | | 1 - 2 | Shooter | Oct 15, 2003 |
| Star Wars Rogue Squadron II: Rogue Leader | GameCube | | 1 | Shooter | Nov 9, 2001 |
| Star Wars: The Clone Wars | GameCube | | 1 - 4 | Action | Oct 28, 2002 |
| Street Hoops | GameCube | | 1 - 2 | Sports | Nov 28, 2002 |
| Street Racing Syndicate | GameCube | | 1 - 4 | Racing | Q3 2004 |
| Strike Force Bowling | GameCube | | 1 - 4 | Sports | Mar 15, 2005 |
| Summoner: A Goddess Reborn | GameCube | | 1 | RPG | Jan 31, 2003 |
| Super Bubble Pop | GameCube | | 1 - 2 | Puzzle | Dec 20, 2002 |
| Super Mario Strikers | GameCube | | 1 - 4 | Sports | Dec 5, 2005 |
| Super Mario Sunshine | GameCube | | 1 | Action | Aug 25, 2002 |
| Super Monkey Ball | GameCube | | 1 - 4 | Action | Nov 17, 2001 |
| Super Monkey Ball 2 | GameCube | | 1 - 4 | Puzzle | Aug 25, 2002 |
| Super Monkey Ball Adventure | GameCube | | 1 - 4 | Adventure | Aug 1, 2006 |
| Super Smash Bros. Melee | GameCube | | 1 - 4 | Fighting | Dec 2, 2001 |
| Surf's Up | GameCube | | 1 - 2 | Sports | Q3 2007 |
| Swingerz Golf | GameCube | | 1 - 4 | Sports | Oct 23, 2002 |
