As bad as the name is, if the Wii U fails to sell to Nintendo's expectations I don't think the name will be the major reason why. I think the single crippling problem with the Wii U is going to be convincing gamers who may currently own a PS3, 360, or PC to buy a console that mainly plays games they can already play on their existing hardware with only minimal improvements. I don't think the call of Nintendo 1st party titles will be enough, not when Nintendo's 1st party software wasn't enough to keep their interest on the Wii. And I just don't see casuals buying this console enough to make up for the multiplatform owners that likely won't cross back.
So what would get such gamers to make a Nintendo console their primary console again? Honestly, I don't know. Tech on par with the next-generation Sony or Microsoft consoles would help, but the Wii U probably won't have anywhere near that. 3rd party exclusives would help, but 3rd parties have moved away from making platform exclusives over this last generation. Exclusive DLC content would help, but Nintendo's not the kind of company to shell out the cash for that sort of thing. A free online service greater than Xbox Live would help, but does anyone really think Nintendo's actually capable of that yet with their low level of experience?
I think the burden of everything really rests on that controller now, and unless that controller is just capable of things we can't even imagine that completely change how we view games (and right now, it doesn't seem so) I just don't know if that'll be enough.