So long as it's an S-Video INPUT (and not OUTput), then yes, it'll work. I've never had a laptop, but I would think that the s-video plug would be an output, so that you could hook up the little laptop to a TV (just a guess). Anyway, if you're sure it's an s-video input, all you'd need to do is get an S-Video connection for your GameCube and you can view the video. As for how you'd listen to the audio... you could probably get some sort of converter at Radio Shack (or somewhere) that'll conver the red & white plugs to a headphone jack.