I just started playing this, and I'm... rather confused by it. There's so much going on, story-wise and control-wise, that I felt completely lost during the first mission. I had no idea where I was going, and I spent so long trying to jump that I eventually looked through the instruction manual and realized that there's no jumping in this game. The battle controls seem needlessly complicated - press X to draw the weapon, LT to zoom in, RT to fire, LB to change weapons, RB to use talents - that's too many buttons!
I've felt like such a gaming noob since I got my 360, because every game I've played, except Assassin's Creed, has been really hard for me. I stopped playing GTA IV because I fail every mission multiple times. I even had a lot of trouble with Beautiful Katamari. I've never failed so many levels in a Katamari game before.
Thank goodness for Uno, otherwise I'd feel like a total loser.