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i still think wesker could start up umbrella here and he infecterd the villagers with a more controled version of the t-virus and made them stop anyone finding the mansion)
That'd be somewhat logical, but from the cinematic between Albert Wesker and William Birkin in Resident Evil Zero, Wesker actually states that he is leaving the Umbrella Corporation for good and will be joining a corporation named the HCF, which stands for either Hive Capture Force or Host Capture Force. It hasn't really clearly been sorted by Capcom. But anyway, seeing that Wesker left Umbrella, there wouldn't be any advantage for him or them if he helps them re-establish their company. If Umbrella
were to come back (which I find relatively doubtful) then I'd presume it'd be Lord Spencer who would re-create his corporation... premusing that he might still be alive.
As for your idea on Resident Evil 5, not much of the Resident Evil storyline would increase except for clearing up a few plot holes from Resident Evil Zero and Resident Evil 1, so I'd find it quite pointless for the game to revolve around the attack on the laboratory... however, this sort of theme may serve relatively good for a Resident Evil side-game. Not a bad idea for a kick-off game, but certainly not for a game that is vital to the story and would need to be numbered.
With Resident Evil 6, it might possibly work out, but it'd be extremely difficult to tie all the STARS members into one game that is situated in Europe... and it'd also be a little out of place. Having the whole mansion-idea with Umbrella possibly inhabbiting it would need to be fitted into Resident Evil 4... not an entirely new game. But once again, not a bad idea for an extension on Resident Evil 4.
And finally, with Resident Evil 7... having a free-roaming environment would be extraordinary as long as it isn't made like an environment that you'd find in an RPG however, 10 cities in total would be a little too much... and the idea of the protagonist returning to the Resident Evil 4 setting would be a little repetitive and might make gamers angry.
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There should be one where you play as the zombie. You are partially resistant and so have the whole phisique but retain your brain and the objective is to kill as many zombies as possible before you totally lose it.
That'd be better off to be used as a mini-game for one of the future Resident Evil's... but for having a game on its own where you play as a person slowly going through zombification wouldn't really be my forte and in the end can be rather pointless. Also, the storyline which doesn't sound like it'd be that advanced might make fan boys angry.