| Name |
System |
Subsystem |
Players |
Genre |
Release Date |
| Sanatory Hallways | Wii U | Download Software | 1 - 2 | Action | Jun 9, 2016 |
| S.C.A.T. | Wii / 3DS / WiiU | VC - NES | 1 - 2 | Action | Dec 4, 2014 |
| Scram Kitty and His Buddy on Rails | Wii U | | | | May 15, 2014 |
| Scribble | Wii U | Download Software | 1 - 8 | Party/Parlor | Dec 15, 2016 |
| Scribblenauts Unlimited | Wii U | | 1 - 5 | Puzzle | Dec 6, 2013 |
| SDK Paint | Wii U | Download Software | 1 | | Feb 26, 2015 |
| SDK Spriter | Wii U | Download Software | 1 | Simulation | Sep 29, 2016 |
| Secret Files: Tunguska | Wii U | Download Software | 1 | Action | Jul 28, 2016 |
| Severed | 3DS / WiiU / Switch | Download Software | 1 | Action | Sep 22, 2016 |
| Shadow Archer | Wii U | Download Software | 1 | Action | Feb 2, 2017 |
| Shadow of the Ninja | Wii / 3DS / WiiU | VC - NES | 1 - 2 | Action | Dec 4, 2014 |
| Shadow Puppeteer | Wii U | Download Software | 1 - 2 | Action | Jan 28, 2016 |
| Shantae: Half-Genie Hero | WiiU / Switch | Download Software | 1 | Action | Dec 20, 2016 |
| Shantae: Risky's Revenge – Director's Cut | Wii U | Download Software | 1 | Action | Mar 24, 2016 |
| Shockman | Wii / WiiU | VC - TG-16 | 1 - 2 | Action | Sep 28, 2017 |
| SHOOT THE BALL | Wii U | Download Software | 1 | Puzzle | Dec 1, 2016 |
| SHOOTY SPACE | Wii U | Download Software | 1 | Action | Sep 15, 2016 |
| Shovel Knight | Wii U | Download Software | 1 | Action | Nov 6, 2014 |
| Sin & Punishment | Wii / WiiU | VC - N64 | 1 - 2 | Action | Sep 3, 2015 |
| Sin & Punishment: Star Successor | Wii / WiiU | VC - Wii | 1 - 2 | Action | Apr 30, 2015 |
| SiNG | Wii U | | 1 - 5 | Party/Parlor | Q4 2012 |
| Sinister Assistant | Wii U | Download Software | 1 | Action | Feb 7, 2019 |
| Six Sides Of The World | Wii U | Download Software | 1 | Puzzle | Mar 23, 2017 |
| Sky Force Anniversary | Wii U | Download Software | 1 - 2 | Shooter | Mar 16, 2017 |
| Skylanders Giants | Wii U | | 1 - 2 | Action | Year 2012 |
| Skylanders SuperChargers | Wii U | | 1 - 2 | Action | Sep 25, 2015 |
| Skylanders: Swap Force | Wii U | | 1 - 2 | Action | Oct 18, 2013 |
| Slender: The Arrival | Wii U | Download Software | 1 | Action | Oct 29, 2015 |
| Soccer | Wii / WiiU | VC - NES | 1 - 2 | Sports | Jun 12, 2014 |
| Soldier Blade | Wii / WiiU | VC - TG-16 | 1 | Shooter | Aug 24, 2017 |
| Solitaire | Wii U | Download Software | 1 | Party/Parlor | Oct 27, 2016 |
| Solomon's Key | Wii / 3DS / WiiU | VC - NES | 1 | Puzzle | May 9, 2013 |
| Sonic & All-Stars Racing Transformed | Wii U | | | Racing | Nov 30, 2012 |
| Sonic Boom: Rise of Lyric | Wii U | | 1 - 4 | Action | Nov 21, 2014 |
| Sonic Lost World | Wii U | | 1 - 2 | | Oct 18, 2013 |
| Soul Axiom | Wii U | Download Software | 1 | Action | Sep 29, 2016 |
| Space Hunted | Wii U | Download Software | 1 | Action | Jun 29, 2017 |
| Spelunker | Wii / 3DS / WiiU | VC - NES | 1 | Action | Jun 6, 2013 |
| Spheroids | Wii U | Download Software | 1 | Action | Jan 5, 2017 |
| Spin the Bottle: Bumpie's Party | Wii U | Download Software | 1 - 8 | Party/Parlor | Aug 8, 2013 |
| SPLASHY DUCK | Wii U | Download Software | 1 | Action | Jun 23, 2016 |
| Splatoon | Wii U | |  | Shooter | May 29, 2015 |
| Spot The Differences: Party! | Wii U | Download Software | 1 - 4 | Party/Parlor | Sep 5, 2013 |
| Spy Chameleon | Wii U | Download Software | 1 | | Dec 25, 2014 |
| Squids Odyssey | Wii U | Download Software | 1 | RPG | May 22, 2014 |
| Star Fox 64 | Wii / WiiU | VC - N64 | 1 - 4 | Shooter | Mar 24, 2016 |
| Star Fox Command | DS / WiiU | VC - DS | 1 | Shooter | Aug 6, 2015 |
| Star Fox Guard | Wii U | | 1 | Action | Apr 22, 2016 |
| Star Fox Zero | Wii U | | 1 - 2 | Action | Apr 22, 2016 |
| Star Ghost | Wii U | Download Software | 1 | Shooter | Mar 10, 2016 |
| Star Sky | Wii U | Download Software | 1 | | Sep 10, 2015 |
| Star Sky 2 | Wii U | Download Software | 1 | Adventure | Apr 14, 2016 |
| Star Splash: Shattered Star | Wii U | Download Software | 1 - 2 | Action | Feb 2, 2017 |
| StarTropics | Wii / WiiU | VC - NES | 1 | Action | Sep 3, 2015 |
| Star Wars Pinball | Wii U | Download Software | 1 - 4 | Party/Parlor | Jul 11, 2013 |
| Starwhal | Wii U | Download Software | 1 - 5 | Action | Oct 8, 2015 |
| Stealth Inc. 2 | Wii U | Download Software | 1 - 2 | Action | Oct 30, 2014 |
| SteamWorld Collection | Wii U | | 1 | Strategy | Sep 30, 2016 |
| SteamWorld Dig | Wii U | Download Software | 1 | Action | Aug 28, 2014 |
| SteamWorld Heist | Wii U | Download Software | 1 | Action | Sep 30, 2016 |
| STEEL LORDS | Wii U | Download Software | 1 - 2 | Fighting | Jun 23, 2016 |
| Steel Rivals | Wii U | Download Software | 1 - 2 | Action | Mar 10, 2016 |
| Stick It to the Man! | Wii U | Download Software | 1 | Action | May 1, 2014 |
| Stone Shire | Wii U | Download Software | 1 | Simulation | Aug 27, 2015 |
| Street Fighter 2010: The Final Fight | 3DS / WiiU | VC - NES | 1 | Action | Dec 18, 2014 |
| Street Fighter Alpha 2 | Wii / 3DS / WiiU | VC - SNES | 1 - 2 | Fighting | Oct 2, 2014 |
| Street Fighter II: The World Warrior | Wii / WiiU | VC - SNES | 1 - 2 | Fighting | Aug 22, 2013 |
| Street Fighter II Turbo: Hyper Fighting | Wii / 3DS / WiiU | VC - SNES | 1 - 2 | Fighting | Aug 22, 2013 |
| Style Boutique | DS / WiiU | VC - DS | 1 | Simulation | Jun 23, 2016 |
| Sudoku and Permudoku | Wii U | Download Software | 1 | Puzzle | Jul 7, 2016 |
| Sudoku Party | 3DS / WiiU | Download Software | 1 - 2 | Puzzle | Mar 23, 2017 |
| Super C | Wii / 3DS / WiiU | VC - NES | 1 - 2 | Action | Jun 19, 2014 |
| Super Castlevania IV | Wii / 3DS / WiiU | VC - SNES | 1 | Action | Oct 31, 2013 |
| Super Dodge Ball | Wii / 3DS / WiiU | VC - NES | 1 - 4 | Action | Mar 13, 2014 |
| Super Ghouls 'n Ghosts | GBA / WiiU | VC - GBA | 1 | Action | Feb 19, 2015 |
| Super Ghouls 'n Ghosts | Wii / 3DS / WiiU | VC - SNES | 1 | Action | May 16, 2013 |
| Super Mario 3D World | Wii U | | 1 - 4 | | Nov 29, 2013 |
| Super Mario 64 | Wii / WiiU | VC - N64 | 1 | Action | Apr 2, 2015 |
| Super Mario 64 DS | DS / WiiU | VC - DS | 1 | Action | Dec 24, 2015 |
| Super Mario Advance | GBA / WiiU | VC - GBA | 1 | Action | Mar 10, 2016 |
| Super Mario Advance 4: Super Mario Bros 3 | GBA / WiiU | VC - GBA | 1 | Action | Mar 10, 2016 |
| Super Mario Bros. | Wii / 3DS / WiiU | VC - NES | 1 - 2 | Action | Sep 12, 2013 |
| Super Mario Bros. 2 | Wii / 3DS / WiiU | VC - NES | 1 | Action | May 16, 2013 |
| Super Mario Bros. 3 | Wii / 3DS / WiiU | VC - NES | 1 - 2 | Action | Dec 26, 2013 |
| Super Mario Bros.: The Lost Levels | Wii / 3DS / WiiU | VC - NES | 1 | Action | Jan 23, 2014 |
| Super Mario Galaxy | Wii / WiiU | VC - Wii | 1 - 2 | Action | Feb 4, 2016 |
| Super Mario Galaxy 2 | Wii / WiiU | VC - Wii | 1 - 2 | Action | Jan 14, 2015 |
| Super Mario Kart | Wii / 3DS / WiiU | VC - SNES | 1 - 2 | Racing | Mar 27, 2014 |
| Super Mario Maker | Wii U | | 1 | | Sep 11, 2015 |
| Super Mario RPG: Legend of the Seven Stars | Wii / WiiU | VC - SNES | 1 | RPG | Dec 24, 2015 |
| Super Mario World | Wii / 3DS / WiiU | VC - SNES | 1 - 2 | Action | Apr 27, 2013 |
| Super Mario World: Super Mario Advance 2 | GBA / WiiU | VC - GBA | 1 | Action | Mar 10, 2016 |
| Super Meat Boy | Wii U | Download Software | 1 | Action | May 12, 2016 |
| Super Metroid | Wii / 3DS / WiiU | VC - SNES | 1 | Adventure | May 16, 2013 |
| Super Paper Mario | Wii / WiiU | VC - Wii | 1 | Action | Aug 11, 2016 |
| Super Punch-Out!! | Wii / 3DS / WiiU | VC - SNES | 1 | Sports | Jun 12, 2014 |
| Super Robo Mouse | Wii U | Download Software | 1 | Puzzle | Apr 7, 2016 |
| Super Smash Bros. for Wii U | Wii U | | 1 - 8 | Fighting | Nov 28, 2014 |
| Super Star Soldier | Wii / WiiU | VC - TG-16 | 1 | Shooter | May 18, 2017 |
| Super Street Fighter II: The New Challengers | Wii / 3DS / WiiU | VC - SNES | 1 - 2 | Fighting | Aug 22, 2013 |
| Super Street Fighter II Turbo Revival | GBA / WiiU | VC - GBA | 1 | Fighting | Jul 16, 2015 |
| Super Toy Cars | Wii U | Download Software | 1 - 4 | Racing | Jul 24, 2014 |
| Super Ultra Star Shooter | Wii U | Download Software | 1 | Shooter | Sep 21, 2017 |
| Suspension Railroad Simulator | Wii U | Download Software | 1 | Simulation | Mar 26, 2015 |
| Swap Blocks | Wii U | Download Software | | Puzzle | Oct 19, 2017 |
| Sweetest Thing | Wii U | Download Software | 1 | Simulation | May 5, 2016 |
| Swords & Soldiers II | Wii U | Download Software | 1 - 2 | Strategy | May 21, 2015 |
