I'm finally experimenting with control alternatives. Right now, I've got:
A: Jump, B: Lock, C: Melee, Z: Fire, L: Crouch, D: Change weapon, R: Zoom, U: Reload, -: Change Grenade, +: ASE, 1: Stats, 2: Pause, Nunchuk: Grenade, Remote: Spin
The bounding box minimized and sensitivities are maximized.
I know it's a little weird to split up the gun controls between two hands, but it means that all of my attacks are now on one hand with easy access. It also frees any potential wobble on my targeting hand except for spinning around, in which case, I wouldn't be on target anyway. I've moved my grip to the D-pad/A instead of A/+/- to facilitate this new scheme.