You guys are mean! OOoooohhh!!!
Anyways, it depends on what type of gamer you are:
A Nintendo gamer would advance straight for Super Paper Mario, do not pass go do not collect 599 US dollars.
A traditional hardcore gamer would appreciate Godfather if they hadn't picked it up yet. It's GTA in the 1950's, but infinitely more playable, more beatable, and with awesome controls where you actually punch, shoot, and strangle with both your hands.
Gamers with a taste for the esoteric, looking for innovation and stuff that can't be found elsewhere, would be intrigued by the quite hardcore surgery sim Trauma Center, or the FPS-turned-suburban-trasure-hunt Elebits. Or even the minigame-esque, totally weird Cooking Mama.
Gamers who want mini-games characterized by wackiness and humor would find Wario Ware right up their alley, and Raving Rabbids marred only by a LOT of clunky menus to navigate.
And there are a couple other games that would suit some players' tastes. Golf fans are apparently buying up Tiger Woods happily. old school gamers don't find much to complain about in Sonic and the Secret Rings. And SSX Blur strikes some people as hard, and others as awesomely natural to snowboard with.