The thing about the Orville is that it doesn't want to replicate TNG with a new paint job which is something I don't think anybody really wants. Enterprise is the example of how dry that well is. I am 100% that Seth could have made straight up TNG and he has the crew to do it and did talk to CBS. To freshen it up, to set it apart, give it the heart that TNG didn't have due to the stiffness of the characters was to make them more real, have them make jokes, flaws, aspirations, regret, grow as people from the get go. It deals with complex social issues in a mature manner without blasting your face and isn't afraid to say "I don't know". TNG never in a 1000 years would have aliens instantly get addicted to cigarettes to show addiction(Disc in funnels anyone?). Seth wrote a love letter to Trek.
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Every John Wick is different enough so not to rehash the last, be new and stay true. Good parodies have that same core. Galaxy Quest is 'Trek', but a comedy, a translation. If it was just a comedy on a space ship it wouldn't be a parody. Spaceballs lovingly mocks SW beyond just having an oversize Vadar helmet. Same with Doc Vadar. The core is that important.
I don't want to derail this thread any further with Orville talk, but it's funny that you decided to bring up Galaxy Quest & Spaceballs. You know what those shows have that The Orville doesn't? Clever writing, satire, and consistency. They are what they are, and they embrace it.
Mel Brooks said on the commentary track for Spaceballs that the key to a good satire is that the story itself has to be good first before you lay on the parody. Spaceballs is a comedy from beginning to end, and for its day quite a clever one (along with some crass humor). It just tells a fun adventure story from beginning to end, skewering silly things about Star Wars, science fiction, and marketing along the way. There's a consistent tone throughout. Galaxy Quest, likewise, has a strong adventure foundation. It starts as a loving parody of how silly the original Star Trek is, and then slowly shifts into a celebration of what that show was before ending on a celebration of the Star Trek fan culture that kept that show alive.
The Orville, on the other hand, doesn't know what it wants to be. 1/2 to 3/4 of the show is comedy so bad that I can't bring myself to care about the characters. Then every once in a while it tries to be serious, but because I was already turned off by the dick jokes, etc. they did with those characters earlier, I don't CARE when the actual pathos happens. It comes off as the writer both being stoned and having ADHD:
"Dicks, though, am I right, brah! But what if...what if that one race we know nothing about...started a war, man! That would be bad, brah! But Dick jokes, right?!"
The Orville is so busy jumping between things that worked for other shows that, IMO, it never establishes a desirable identity of its own. And I know a lighter-style sci-fi show with serious drama CAN work because Farscape and the StarGate franchise pulled it off. They just had better writers. The Orville wants to do smart science fiction without actually being smart. It wants deep pathos without actually earning it.