I'm behind on podcasts, so forgive the late comments.
Eternal Darkness' environments made up one of my favorite parts of the game. Seeing how the recurring locales changed was really neat. It would be cool to see that worked into another game.
I agree with Jonny and co. about the game being on a "true" adult level. I'd love more "grown-up" games with stories and content that only an adult could appreciate. I used to enjoy gratuitous violence and gore in my games, but now it's almost a turn-off.
I didn't replay ED for this edition of RetroActive, but listening to the podcast has reminded me how much great stuff was in the game. (No wonder I bothered to play through it all three times when it came out...)
Oh, and the added insanity effects were an awesome touch - they really had me for a minute, there!
P.S. Holy shiz I remember Hercules in NY. I think it was on TV or something years ago. Terrible.