3DS - Nintendo
Rhythm Tengoku The Best +, I doubt the game will show up at E3 but I swear to God I will weep salty tears if it slips due to the NX in 2016.
Girls Mode 3 - This may show up although I don't think the digital event is the right time and or place to announce such a game, may be stealth announced like Mario Party was last year.
Fire Emblem IF - I think this will be absent, it is too close to the Japanese release and too far away from the English release, will probably get it's own direct.
Mother 3D - Call me a starmen.net conspiracist but I think Mother 3D is an absolute lock for E3. It has been teased at least twice by NCL/NOA, Iwata said to expect more remakes on 3DS and Lucas comes out in June, the month of E3. Coincidence? I think not.
The Great Detective Pikachu - Assuming this hasn't been cancelled this could show up in whatever hideous form it has taken.
Pokemon - There are 3 ways Pokemon could go at this point; Pokemon 7, Pokemon Z, Pokemon Remake. It'll probably be at E3, or they could pull another 2014 and announce it on May 7th.
3DS - Atlus
Etrian Odyssey Untold 2 - I'm sure this will be there just not in the presentation.
Legend Of Legacy - I'm sure this will be there, Nintendo gave it a big push in Japan and I assume the same will happen here.
Stella Glow - Not exactly main show material but you never know.
Etrian Odyssey 5 - Too soon.
3DS - Bandai Namco
Project X Zone 2 - This will certainly show up in some capacity since it comes out so soon.
Dragon Ball Z: Extreme Butouden - Maybe? Who knows.
3DS - Square Enix
Final Fantasy Explorers - Considering how well MH4U did in the west it may come over, especially since it has the Final Fantasy name attached.
Bravely Default 2 - The first did well so I assume the second will come over in 2016.
Dragon Quest 7 - Nope.
3DS - Level 5
Yokai Watch - This will show up without a doubt considering it's being published by Nintendo and coming early 2016.
Snack World - I don't really see this leaving Japan to be honest.
3DS - Capcom
Monster Hunter Stories - We'll probably get a trailer on May 31st but not at E3.
The Great Ace Attorney - I really hope this gets localised but may faith is dwindling, Plz Capcom!
3DS - Koei Tecmo
Atelier Rorona Plus - I imagine James would have fun reviewing this.
3DS - Others
Zero Escape 3 - This will most likely be announced at E3 since it has been teased heavily and sold better in the west.
Langrisser - So niche it'll probably never come, but we'll see.
Lord of Magna - We know it's coming but not exactly E3 material.
Corpse Party 3DS - XSeed will most likely bring this over.
Wii U - Nintendo
Xenoblade X - This game will be released on the 20th November 2015, it is Nintendo's biggest game this year and needs prime time if they want to recoup costs.
Mario Maker - Will be released September, playable but not show.
Yoshi's Woolly World - Absent, nothing to show or tell any more.
Star Fox - Miyamoto's glorious return to form. December 2015.
Retro Studio's New Project - Way too soon, maybe teased but won't be shown.
Next Level's New Project - This studio has been too silent for too long, whatever they are working on it's big, announced at E3 released 1st half 2016.
Devil's Third - Itagaki said the game is finished so it'll certainly show up.
Animal Crossing Wii U - Probably in development to be released 27th May 2016
Zelda Wii U - Absent, the more they show this year the less they can show next year. Release 18th November 2016.
Wii U -Atlus
Shin Megami Tensei X Fire Emblem - This will certainly be at E3, new trailer and treehouse demo. November for Japan, sometime in late 2016 for the west.
Wii U - Bandai Namco
Project Treasure - A very intriguing game, It must be funded by Nintendo and probably release 2016.
Pokken - Will be announced and released in 2016 I think, too early for a console port.
Wii U - Square Enix
Dragon Quest 10 - Nope, not even anything on the virtual console outside of Japan.
Wii U - Level 5
Nothing
Wii U - Capcom
Monster Hunter 4UU - They sent out a survey gauging interest in a Wii U version but I doubt anything will come of it.
Wii U - Koei Tecmo
Fatal Frame 5 - People seem to have forgotten this but there is going to be a western fatal frame movie by the Resident Evil director. The movie and game will most likely be out in September 2015.
Wii U - Other
Rodea the Sky Soldier - Out in September by Yuji Naka and Prope. Hopefully Nintendo put some advertising behind it and don't just sent it out to die.
Tantalus's Wii U Project - No idea.
Fast Racing Neo - Confirmed for E3
Guitar Hero Live - Will probably be mentioned once.
Lego Games - **** tons of lego games as far as the eye can see.
That's about it, but I am also interested in the account system DeNa is setting up. Hopefully there is a reward program similar to digital deluxe where the more games you buy the cheaper the games become.