It looks to be a summation of the series along with new stuff. I see microgames I recognize from the first 3 games along with new ones mixed in. The only title they may exclude things from is Smooth Moves depending on the games which relied on the Wiimote motion controls although having the gyroscope controls might allow them to work with a slight tweak. The 3DS can do everything the original version did, what Twisted did thanks to the gyro controls and what Touched and D.I.Y. did on the DS. So, I'm glad that they are realizing the amount of different controls and commands or playstyles can be done with the DS and are incorporating them all like this instead of the sort of themed or demo like experiences normally put out by the series. Sadly, this may be the biggest 3DS game getting released this year that I'm excited about but maybe E3 will pull off a big surprise reveal like Samus Returns last year.
Also, you should really give the WarioWare series a shot, especially the first game (although I did like Twisted a lot and recommended it as a title for NWR's Hall of Fame but it's a bit harder to get a hold of. Speaking of the Hall, anyone know when they were going to announce the next inductees?)